A measure space approach to optimal source placement

A measure space approach to optimal source placement

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Article ID: iaor20125337
Volume: 53
Issue: 1
Start Page Number: 155
End Page Number: 171
Publication Date: Sep 2012
Journal: Computational Optimization and Applications
Authors: ,
Keywords: medicine
Abstract:

The problem of optimal placement of point sources is formulated as a distributed optimal control problem with sparsity constraints. For practical relevance, partial observations as well as partial and non‐negative controls need to be considered. Although well‐posedness of this problem requires a non‐reflexive Banach space setting, a primal‐predual formulation of the optimality system can be approximated well by a family of semi‐smooth equations, which can be solved by a superlinearly convergent semi‐smooth Newton method. Numerical examples indicate the feasibility for optimal light source placement problems in diffusive photochemotherapy.

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