 
                                                                                | Article ID: | iaor2006438 | 
| Country: | United Kingdom | 
| Volume: | 18 | 
| Issue: | 5 | 
| Start Page Number: | 376 | 
| End Page Number: | 385 | 
| Publication Date: | Jul 2005 | 
| Journal: | International Journal of Computer Integrated Manufacturing | 
| Authors: | Dolgui A., Levin G., Louly M.-A. | 
| Keywords: | supply chain, lot sizing | 
The paper addresses a problem of optimal lot-sizing and sequencing of manufacturing items for production lines. The following factors are taken into account: processing times, set-up times, random machine breakdowns and rejects. The goal is to maximize the probability of a desired output for a given period. A mathematical model of the problem and an optimization approach are discussed. This approach is based on the decomposition of the initial problem in three subproblems: an enumeration, a travelling salesman problem and a knapsack problem. An iterative optimization procedure is proposed, based on this decomposition.