Heterogeneity in epidemic models and its effect on the spread of infection

Heterogeneity in epidemic models and its effect on the spread of infection

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Article ID: iaor2000589
Country: United Kingdom
Volume: 35
Issue: 3
Start Page Number: 651
End Page Number: 661
Publication Date: Sep 1998
Journal: Journal of Applied Probability
Authors: ,
Keywords: medicine
Abstract:

We first study an epidemic amongst a population consisting of individuals with the same infectivity but with varying susceptibilities to the disease. The asymptotic final epidemic size is compared with the corresponding size for a homogeneous population. Then we group a heterogeneous population into households, assuming very high infectivity within households, and investigate how the global infection pressure is affected by rearranging individuals between the households. In both situations considered, it turns out that whether or not homogenizing the individuals or households will result in an increased spread of infection actually depends on the infectiousness of the disease.

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