A convergence theorem for Markov chains arising in population genetics and the coalescent with selfing

A convergence theorem for Markov chains arising in population genetics and the coalescent with selfing

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Article ID: iaor19992529
Country: United Kingdom
Volume: 30
Issue: 2
Start Page Number: 493
End Page Number: 512
Publication Date: Jun 1998
Journal: Advances in Applied Probability
Authors:
Keywords: stochastic processes
Abstract:

A simple convergence theorem for sequences of Markov chains is presented in order to derive new ‘convergence-to-the-coalescent’ results for diploid neutral population models. For the so-called diploid Wright-Fisher model with selfing probability s and mutation rate θ, it is shown that the ancestral structure of n sampled genes can be treated in the framework of an n-coalescent with mutation rate θ∼ :=θ(1 – s/2), if the population size N is large and if the time is measured in units of (2 – s)N generations.

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