Article ID: | iaor201530752 |
Volume: | 274 |
Start Page Number: | 125 |
End Page Number: | 132 |
Publication Date: | Feb 2016 |
Journal: | Applied Mathematics and Computation |
Authors: | Berntsson Fredrik, Karlsson Matts, Kozlov Vladimir, Nazarov Sergey A |
Keywords: | simulation, networks: flow, numerical analysis, biology |
In this paper we present a one‐dimensional model of blood flow in a vessel segment with an elastic wall consisting of several anisotropic layers. The model involves two variables: the radial displacement of the vessel’s wall and the pressure, and consists of two coupled equations of parabolic and hyperbolic type. Numerical simulations on a straight segment of a blood vessel demonstrate that the model can produce realistic flow fields that may appear under normal conditions in healthy blood vessels; as well as flow that could appear during abnormal conditions. In particular we show that weakening of the elastic properties of the wall may provoke a reverse blood flow in the vessel.