Using data mining to identify structural rules in proteins

Using data mining to identify structural rules in proteins

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Article ID: iaor20118971
Volume: 218
Issue: 5
Start Page Number: 1997
End Page Number: 2004
Publication Date: Nov 2011
Journal: Applied Mathematics and Computation
Authors: , ,
Keywords: datamining, statistics: inference
Abstract:

The progress in bioinformatics and biotechnology area has generated a huge amount of sequences that requires a detailed analysis. There are several data mining techniques that can be used to discovery patterns in large databases. This paper describes the development of a tool/methodology to extract hydrophobicity patterns/profiles that archives a specific secondary structure in proteins. The results indicate that association rules can be efficient method to investigate this kind of problem. This work contributes for two areas: prediction of protein structure and protein folding.

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