Dynamics and application of an epidemiological model for hepatitis C

Dynamics and application of an epidemiological model for hepatitis C

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Article ID: iaor20124015
Volume: 56
Issue: 1-2
Start Page Number: 36
End Page Number: 42
Publication Date: Jul 2012
Journal: Mathematical and Computer Modelling
Authors: ,
Keywords: simulation
Abstract:

An epidemiological model for the spread of hepatitis C equ1 is developed and discussed. The analysis indicates that the eradication or persistence of the disease is completely determined by the magnitude of the basic reproductive number R 0 equ2. The dynamical analysis reveals that the disease free equilibrium of the model is globally asymptotically stable if R 0 equ3 is less than unity. On the other hand, if R 0 > 1 equ4 and the HCV induced death rate is not considered, the unique endemic equilibrium is globally asymptotically stable under certain conditions. Numerical simulations are performed to investigate the influence of different vital parameters on HCV prevalence. Based on the available HCV epidemic data in China, the model is applied to simulate the HCV transmission in the future.

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