Global Dynamics of a Tuberculosis Epidemic Model and the Influence of Backward Bifurcation

Global Dynamics of a Tuberculosis Epidemic Model and the Influence of Backward Bifurcation

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Article ID: iaor20127243
Volume: 11
Issue: 4
Start Page Number: 433
End Page Number: 459
Publication Date: Dec 2012
Journal: Journal of Mathematical Modelling and Algorithms
Authors: ,
Keywords: simulation
Abstract:

In this paper, we propose and analyze a tuberculosis (TB) model with exogenous re‐infection. We assume that treated individual may be again infected by infectious individual. The model exhibits two bifurcations viz. transcritical bifurcation when the basic reproductive number R 0 = 1 and backward bifurcation where the disease transmission rate β plays as control parameter. The persistent of the model and, the local and global stability criteria of disease‐free and endemic equilibria are discussed. By carrying out bifurcation analysis, it is shown that the model exhibits the bistability and undergoes the Hopf bifurcation when immunological memory is everlasting i.e. when σ = 0. Lastly, some simulations are given to verify our analytical results.

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