Finding global optimum of a non-convex quadratic function is in general a very difficult task even when the feasible set is a polyhedron. We show that when the feasible set of a quadratic problem consists of orthogonal matrices from Rn×k , then we can transform it into a semidefinite program in matrices of order kn which has the same optimal value. This opens new possibilities to get good lower bounds for several problems from combinatorial optimization, like the Graph partitioning problem (GPP), the Quadratic assignment problem (QAP), etc. In particular we show how to improve significantly the well-known Donath-Hoffman eigenvalue lower bound for GPP by semidefinite programming. In the last part of the paper we show that the copositive strengthening of the semidefinite lower bounds for GPP and QAP yields the exact values.