Policies for biodefense revisited: The prioritized vaccination process for smallpox

Policies for biodefense revisited: The prioritized vaccination process for smallpox

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Article ID: iaor20072427
Country: Netherlands
Volume: 148
Issue: 1
Start Page Number: 5
End Page Number: 23
Publication Date: Nov 2006
Journal: Annals of Operations Research
Authors:
Keywords: simulation: applications, health services
Abstract:

Handling bioterror events that involve contagious agents is a major concern for authorities and a cause for debate among policymakers about the best response policy. At the core of this debate stands the question which of the two post-event policies to adopt: mass vaccination or trace (also called ring or targeted) vaccination. We present a new dynamic epidemic-intervention model that captures key features of the situation and generalizes some previous assumptions regarding the probability distributions of inter-temporal parameters. It is shown that a mixture of mass and trace vaccination policies – the prioritized vaccination policy – is more effective than either of the two aforementioned policies.

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