This article deals with an inventory problem where the supply is available only during an interval of (random) length X. The unavailability of supply lasts for a random duration Y. Using concepts from renewal theory, the authors construct an objective function (average cost/time) in terms of the order-quantity decision variable Q. We develop the individual cost components as order, holding, and shortage costs after introducing two important random variables. Due to the complexity of the objective function when X and Y are general random variables, the authors discuss two special cases and provide numerical examples with senstivity analysis on the cost and noncost parameters. The article concludes with a discussion of the comparison of the current model with random yield and random lead-time models. Suggestions for further research are also provided.