A qualitative study of a vaccination model with non-linear incidence

A qualitative study of a vaccination model with non-linear incidence

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Article ID: iaor2005268
Country: United States
Volume: 143
Issue: 2/3
Start Page Number: 409
End Page Number: 419
Publication Date: Nov 2003
Journal: Applied Mathematics and Computation
Authors: ,
Keywords: epidemiology, vaccination
Abstract:

We propose a new deterministic model for the dynamics of an infectious disease in the presence of a preventive (prophylactic) vaccine and an effective therapeutic treatment. The three-dimensional model, which assumes a non-linear incidence rate, is analysed qualitatively to determine the stability of its equilibria. The optimal vaccine coverage threshold needed for disease control and eradication is determined analytically (and verified using numerical simulations). The case where no vaccination is given (vaccination-free model) is also investigated. Using a Dulac function, it is shown that the vaccination-free model has no limit cycles.

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