Convergence to stationarity in the Moran model

Convergence to stationarity in the Moran model

0.00 Avg rating0 Votes
Article ID: iaor2004885
Country: United States
Volume: 37
Issue: 3
Start Page Number: 705
End Page Number: 717
Publication Date: Sep 2000
Journal: Journal of Applied Probability
Authors: ,
Keywords: biology
Abstract:

Consider a population of fixed size consisting of N haploid individuals. Assume that this population evolves according to the two-allele neutral Moran model in mathematical genetics. Denote the two alleles by A1 and A2. Allow mutation from one type to another and let 0 < γ < 1 be the sum of mutation probabilities. All the information about the population is recorded by the Markov chain X = (X (t))t≥0 which counts the number of individuals of type A1. In this paper we study the time taken for the population to ‘reach’ stationarity (in the sense of separation and total variation distances) when initially all individuals are of one type. We show that after t* = N γ−1 log N + cN the separation distance between the law of X(t*) and its stationary distribution converges to 1 − exp(−γeγ c) as N → ∞. For the total variation distance an asymptotic upper bound is obtained. The results depend on a particular duality, and couplings, between X and a genealogical process known as the lines of descent process.

Reviews

Required fields are marked *. Your email address will not be published.