Using an integer programming model to determine the price of combination vaccines for childhood immunization

Using an integer programming model to determine the price of combination vaccines for childhood immunization

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Article ID: iaor20033218
Country: Netherlands
Volume: 119
Issue: 1
Start Page Number: 261
End Page Number: 284
Publication Date: Mar 2003
Journal: Annals of Operations Research
Authors: ,
Keywords: programming: integer
Abstract:

The Recommended Childhood Immunization Schedule has become sufficiently crowded that the prospect of adding additional vaccines to this schedule may not be well received by either health-care providers or parents/guardians. This has encouraged vaccine manufacturers to develop combination vaccines that can permit new vaccines to be added to the schedule without requiring children to be exposed to an unacceptable number of injections during a single clinic visit. This paper develops an integer programming model to assess the economic premium that exists in having combination vaccines available. The results of this study suggest that combination vaccines provide a cost effective alternative to individual vaccines and that further developments and innovations in this area by vaccine manufacturers can provide significant economic and societal benefits.

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