| Article ID: | iaor20022833 |
| Country: | Netherlands |
| Volume: | 138 |
| Issue: | 2 |
| Start Page Number: | 452 |
| End Page Number: | 458 |
| Publication Date: | Apr 2002 |
| Journal: | European Journal of Operational Research |
| Authors: | Ecker J.G., Kupferschmid M., Lawrence C.E., Reilly A.A., Scott A.C.H. |
| Keywords: | programming: mathematical |
A maximum likelihood approach has been proposed for finding protein binding sites on strands of DNA. We formulate an optimization model for the problem and present calculations with experimental sequence data to study the behavior of this site identification method.