Network designers for many transportation or telecommunication applications need to minimize the maximum (weighted) interaction time or distance in the networks, i.e., to solve the p-hub center problems. This study addresses the p-hub center problem. A single-relocation heuristic is proposed as a means of generating location–allocation strategies in a reasonable amount of time, and tabu search is superimposed on the underlying algorithm, so as to decrease the possibility of being trapped by local optima. Two single-allocation schemes are adapted from the literature, and a further one is developed specifically for the minimax objective function, for use in the evaluation phase of the algorithm. A greedy local search is employed to improve the resulting allocations. A number of strategies for choosing the initial hub locations are discussed and initial strategy–allocation scheme combinations are compared in terms of solution quality and pragmatic efficiency.