Comparison of test vs. control treatments using distance optimality criterion

Comparison of test vs. control treatments using distance optimality criterion

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Article ID: iaor20013690
Country: Germany
Volume: 52
Issue: 2
Start Page Number: 147
End Page Number: 162
Publication Date: Jan 2000
Journal: Metrika
Authors: , ,
Abstract:

We consider the problem of comparison of one test treatment (τ0) with a set of υ control treatments (τ1, τ2, ..., τυ) using distance optimality (DS-optimality) criterion introduced by Sinha in some treatment-connected design settings. It turns out that the nature of DS-optimal designs is quite similar to that for the usual A-, D- and E-optimality criteria. However, the optimality problem is quite complicated in most situations. First we deal with the CRD model and derive DS-optimal allocations for a given set of treatments. The results are almost identical to the A-optimal allocations for such problems. Then we consider a block design set-up and examine the nature of DS-optimal designs. In the process, we introduce the method of weighted coverage probability and maximize the resulting expression to obtain an optimal design.

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