We used a linear programming model to estimate the financial returns to a Staphylococcus aureus testing and control program over a 1-year period for a 100-cow herd, with a 8636-kg rolling-herd average. Six tests, which vary in sensitivity from 0.80 to 0.98 and specificity of 0.99, were examined in simulated herds with 10, 20 and 30% prevalence of S. aureus infection. Sensitivity of these results to a range of assumptions regarding rolling-herd average, milk price, somatic cell-count (SCC) premium, and cost and cure rate of dry treatment were examined to determine the profits from the program. The profits of a control program are most dependent upon prevalence, cell-count premium, and cost of dry treatment. In our simulation for a 100-cow herd, a testing and control program appears to cost less than US10 per cow per year, and pays for itself within 1 yr, except under the lowest prevalence and most-adverse conditions (low yield, high cost of dry treatment, or low SCC premium).
