In this paper the effect of the break quantity rule on the inventory costs in a 1-warehouse, N-retailers distribution system is analyzed. The break quantity rule is to deliver large orders from the warehouse, and small orders from the nearest retailer, where a so-called break quantity determines whether an order is small or large. Under the assumptions that the stock at the warehouse can only be used to satisfy large orders, and that demand during the lead times is normally distributed, an expression for the inventory costs is derived. The objective of this paper is to provide insight into the effect of the break quantity rule on the inventory holding costs, and therefore we present extensive computational results, showing that in many cases the rule leads to a significant cost reduction.