Nonlinear regression and curved exponential families. Improvement of the approximation to the asymptotic distribution

Inference in nonlinear models is usually based on the asymptotic normal distribution, based on linearizing the model. The accuracy of this approximation can in many cases be improved by a reparametrization. Systematic methods for doing this will be described. Sometimes a saddlepoint approximation can be used, and this offers several advantages compared to the asymptotic distribution and the Edgeworth expansion. The improved methods are unfortunately not commonly used. It will be discussed why this is so. The methods will be illustrated by a series of examples.