In an ergodic network of K M/M/1 queues in series the paper considers the rate event that, as N increases, the total population in the network exceeds N during a busy period. By utilizing the contraction principle of large deviation theory, an action functional is obtained for this exit problem. The ensuing minimization is carried out for K=2 and an indication is given for arbitrary K. It is shown that, asymptotically and for unequal service rates, the ‘most likely’ path for this rare event is one where the arrival rate has been interchanged with the smallest service rate. The problem has been posed in Parekh and Walrand in connection with importance sampling simulation methods for queueing networks. Its solution has previously been obtained only heuristically.